SYNTHESIS AND ANTIMICROBIAL EVALUATION OF QUINAZOLINONE PEPTIDE DERIVATIVES

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Synthesis of Some New Quinazolinone Derivatives and Evaluation of Their Antimicrobial Activities

Wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. Anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. Deoxyvasicinone which wa...

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Synthesis of Some New Quinazolinone Derivatives and Evaluation of Their Antimicrobial Activities

Wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. Anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. Deoxyvasicinone which wa...

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Synthesis of Some New Quinazolinone Derivatives and Evaluation of Their Antimicrobial Activities

WIDE RANGE OF QUINAZOLINONE BIOLOGICAL PROPERTIES INCLUDING antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. Anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. Deoxyvasicinone which was...

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Heterocyclic scaffold including nitrogen, sulfur and oxygen has been under exploration due to their significant therapeutic and medicinal properties. Among these types of molecules, 4thiazolidinones have displayed various important biological activities. Especially rhodanine (2-thioxothiazolidine-4-ones) derivatives represent privileged scaffolds in drug discovery, due to the presence of >N–C–S...

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synthesis of some new quinazolinone derivatives and evaluation of their antimicrobial activities

wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. deoxyvasicinone which wa...

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ژورنال

عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research

سال: 2017

ISSN: 2455-3891,0974-2441

DOI: 10.22159/ajpcr.2017.v10s4.21329